| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 29-5-21 18:30 | CD Teneriffa | Real Oviedo | 2:2 |
| 30-5-21 18:30 | Albacete Balompie | CF Fuenlabrada | 1:2 |
| 30-5-21 21:00 | CD Mirandes | CD Sabadell | 0:2 |
| 30-5-21 21:00 | FC Cartagena | FC Girona | 1:1 |
| 30-5-21 21:00 | Rayo Vallecano | CD Lugo | 0:1 |
| 30-5-21 21:00 | FC Malaga | CD Castellon | 3:0 |
| 30-5-21 21:00 | SD Ponferradina | RCD Mallorca | 2:2 |
| 30-5-21 21:00 | AD Alcorcon | Espanyol Barcelona | 1:0 |
| 30-5-21 21:00 | UD Logrones | UD Las Palmas | 0:1 |
| 30-5-21 21:00 | Real Saragossa | CD Leganes | 0:5 |
| 30-5-21 21:00 | Sporting Gijon | UD Almeria | 0:2 |