| Eastern Conference | Gesp | Pnt | Doelpunten | Vers | W | G | v | |
|---|---|---|---|---|---|---|---|---|
| 1. | New York City FC | 34 | 64 | 63:42 | 21 | 18 | 10 | 6 |
| 2. | Atlanta United FC | 34 | 58 | 58:43 | 15 | 18 | 4 | 12 |
| 3. | Philadelphia Union | 33 | 54 | 56:48 | 8 | 16 | 6 | 11 |
| 4. | Toronto FC | 34 | 50 | 57:52 | 5 | 13 | 11 | 10 |
| 5. | D.C. United | 34 | 50 | 42:38 | 4 | 13 | 11 | 10 |
| 6. | New York Red Bulls | 34 | 48 | 53:51 | 2 | 14 | 6 | 14 |
| 7. | New England Revolution | 34 | 45 | 50:57 | -7 | 11 | 12 | 11 |
| 8. | Chicago Fire | 34 | 42 | 55:47 | 8 | 10 | 12 | 12 |
| 9. | CF Montreal | 34 | 41 | 47:60 | -13 | 12 | 5 | 17 |
| 10. | Columbus Crew | 34 | 38 | 39:47 | -8 | 10 | 8 | 16 |
| 11. | Orlando City | 33 | 36 | 42:50 | -8 | 9 | 9 | 15 |
| 12. | FC Cincinnati | 34 | 24 | 31:75 | -44 | 6 | 6 | 22 |
| Western Conference | Gesp | Pnt | Doelpunten | Vers | W | G | v | |
|---|---|---|---|---|---|---|---|---|
| 1. | Los Angeles FC | 34 | 72 | 85:37 | 48 | 21 | 9 | 4 |
| 2. | Seattle Sounders | 34 | 56 | 52:49 | 3 | 16 | 8 | 10 |
| 3. | Minnesota United FC | 34 | 53 | 52:43 | 9 | 15 | 8 | 11 |
| 4. | Real Salt Lake | 34 | 53 | 46:41 | 5 | 16 | 5 | 13 |
| 5. | Los Angeles Galaxy | 34 | 51 | 58:59 | -1 | 16 | 3 | 15 |
| 6. | Portland Timbers | 34 | 49 | 52:49 | 3 | 14 | 7 | 13 |
| 7. | FC Dallas | 34 | 48 | 54:46 | 8 | 13 | 9 | 12 |
| 8. | San Jose Earthquakes | 34 | 44 | 52:55 | -3 | 13 | 5 | 16 |
| 9. | Colorado Rapids | 34 | 42 | 58:63 | -5 | 12 | 6 | 16 |
| 10. | Houston Dynamo | 34 | 40 | 49:59 | -10 | 12 | 4 | 18 |
| 11. | Sporting Kansas City | 34 | 38 | 49:67 | -18 | 10 | 8 | 16 |
| 12. | Vancouver Whitecaps | 34 | 34 | 37:59 | -22 | 8 | 10 | 16 |