| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 22-2-25 20:30 | Inter Miami CF | New York City FC | -:- |
| 22-2-25 22:30 | Los Angeles FC | Minnesota United FC | -:- |
| 23-2-25 1:30 | Orlando City | Philadelphia Union | -:- |
| 23-2-25 1:30 | D.C. United | Toronto FC | -:- |
| 23-2-25 1:30 | Columbus Crew | Chicago Fire | -:- |
| 23-2-25 1:30 | FC Cincinnati | New York Red Bulls | -:- |
| 23-2-25 1:30 | Atlanta United FC | CF Montreal | -:- |
| 23-2-25 2:30 | St. Louis City SC | Colorado Rapids | -:- |
| 23-2-25 2:30 | Nashville SC | New England Revolution | -:- |
| 23-2-25 2:30 | Houston Dynamo | FC Dallas | -:- |
| 23-2-25 2:30 | Austin FC | Sporting Kansas City | -:- |
| 23-2-25 4:30 | Seattle Sounders | Charlotte FC | -:- |
| 23-2-25 4:30 | San Jose Earthquakes | Real Salt Lake | -:- |
| 23-2-25 22:00 | Portland Timbers | Vancouver Whitecaps | -:- |
| 24-2-25 1:00 | Los Angeles Galaxy | San Diego FC | -:- |