| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 11-12-24 16:30 | Fenerbahce Istanbul | Athletic Bilbao | 0:2 |
| 12-12-24 18:45 | Malmö FF | Galatasaray Istanbul | 2:2 |
| 12-12-24 18:45 | AS Rom | Sporting Braga | 3:0 |
| 12-12-24 18:45 | PAOK Saloniki | Ferencvárosi TC | 5:0 |
| 12-12-24 18:45 | Olympiakos Piräus | FC Twente Enschede | 0:0 |
| 12-12-24 18:45 | Royale Union Saint-Gilloise | OGC Nice | 2:1 |
| 12-12-24 18:45 | PFC Ludogorets Razgrad | AZ Alkmaar | 2:2 |
| 12-12-24 18:45 | Viktoria Pilsen | Manchester United | 1:2 |
| 12-12-24 18:45 | 1899 Hoffenheim | FCSB Bukarest | 0:0 |
| 12-12-24 21:00 | Glasgow Rangers | Tottenham Hotspur | 1:1 |
| 12-12-24 21:00 | FC Porto | FC Midtjylland | 2:0 |
| 12-12-24 21:00 | Slavia Prag | RSC Anderlecht | 1:2 |
| 12-12-24 21:00 | Ajax Amsterdam | Lazio Rom | 1:3 |
| 12-12-24 21:00 | Maccabi Tel Aviv | Rigas Futbola Skola | 2:1 |
| 12-12-24 21:00 | Real Sociedad | Dynamo Kiew | 3:0 |
| 12-12-24 21:00 | Olympique Lyon | Eintracht Frankfurt | 3:2 |
| 12-12-24 21:00 | FK Bodö/Glimt | Besiktas Istanbul | 2:1 |
| 12-12-24 21:00 | IF Elfsborg Boras | Qarabag | 1:0 |