| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 28-11-24 18:45 | Lazio Rom | PFC Ludogorets Razgrad | -:- |
| 28-11-24 18:45 | Dynamo Kiew | Viktoria Pilsen | -:- |
| 28-11-24 18:45 | Qarabag | Olympique Lyon | -:- |
| 28-11-24 18:45 | Besiktas Istanbul | Maccabi Tel Aviv | -:- |
| 28-11-24 18:45 | Rigas Futbola Skola | PAOK Saloniki | -:- |
| 28-11-24 18:45 | RSC Anderlecht | FC Porto | -:- |
| 28-11-24 18:45 | Athletic Bilbao | IF Elfsborg Boras | -:- |
| 28-11-24 18:45 | AZ Alkmaar | Galatasaray Istanbul | -:- |
| 28-11-24 21:00 | Slavia Prag | Fenerbahce Istanbul | -:- |
| 28-11-24 21:00 | Manchester United | FK Bodö/Glimt | -:- |
| 28-11-24 21:00 | Tottenham Hotspur | AS Rom | -:- |
| 28-11-24 21:00 | Ferencvárosi TC | Malmö FF | -:- |
| 28-11-24 21:00 | Sporting Braga | 1899 Hoffenheim | -:- |
| 28-11-24 21:00 | Real Sociedad | Ajax Amsterdam | -:- |
| 28-11-24 21:00 | FC Midtjylland | Eintracht Frankfurt | -:- |
| 28-11-24 21:00 | FCSB Bukarest | Olympiakos Piräus | -:- |
| 28-11-24 21:00 | OGC Nice | Glasgow Rangers | -:- |
| 28-11-24 21:00 | FC Twente Enschede | Royale Union Saint-Gilloise | -:- |