Speelschema
| Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|
| 22-10-21 20:30 | 22-10-21 20:30 | FSV Mainz 05 | FC Augsburg | 4:1 | 2 - 6 - 8 |
| 23-10-21 15:30 | 23-10-21 15:30 | RB Leipzig | SpVgg Greuther Fürth | 4:1 | 2 - 8 - 8 |
| 23-10-21 15:30 | 23-10-21 15:30 | FC Bayern München | 1899 Hoffenheim | 4:0 | 2 - 8 - 8 |
| 23-10-21 15:30 | 23-10-21 15:30 | Arminia Bielefeld | Borussia Dortmund | 1:3 | 8 - 8 - 2 |
| 23-10-21 15:30 | 23-10-21 15:30 | VfL Wolfsburg | SC Freiburg | 0:2 | 3 - 3 - 4 |
| 23-10-21 18:30 | 23-10-21 18:30 | Hertha BSC | Bor. Mönchengladbach | 1:0 | 5 - 4 - 3 |
| 24-10-21 15:30 | 24-10-21 15:30 | 1. FC Köln | Bayer 04 Leverkusen | 2:2 | 6 - 5 - 3 |
| 24-10-21 17:30 | 24-10-21 17:30 | VfB Stuttgart | 1. FC Union Berlin | 1:1 | 3 - 4 - 3 |
| 24-10-21 19:30 | 24-10-21 19:30 | VfL Bochum | Eintracht Frankfurt | 2:0 | 5 - 5 - 3 |