Speelschema
| Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|
| 25-2-22 20:30 | 25-2-22 20:30 | 1899 Hoffenheim | VfB Stuttgart | 2:1 | 2 - 8 - 8 |
| 26-2-22 15:30 | 26-2-22 15:30 | SC Freiburg | Hertha BSC | 3:0 | 2 - 8 - 8 |
| 26-2-22 15:30 | 26-2-22 15:30 | Bor. Mönchengladbach | VfL Wolfsburg | 2:2 | 3 - 4 - 4 |
| 26-2-22 15:30 | 26-2-22 15:30 | 1. FC Union Berlin | FSV Mainz 05 | 3:1 | 4 - 4 - 3 |
| 26-2-22 15:30 | 26-2-22 15:30 | Bayer 04 Leverkusen | Arminia Bielefeld | 3:0 | 2 - 8 - 8 |
| 26-2-22 15:30 | 26-2-22 15:30 | SpVgg Greuther Fürth | 1. FC Köln | 1:1 | 6 - 5 - 3 |
| 26-2-22 18:30 | 26-2-22 18:30 | Eintracht Frankfurt | FC Bayern München | 0:1 | 8 - 8 - 2 |
| 27-2-22 15:30 | 27-2-22 15:30 | VfL Bochum | RB Leipzig | 0:1 | 8 - 6 - 2 |
| 27-2-22 17:30 | 27-2-22 17:30 | FC Augsburg | Borussia Dortmund | 1:1 | 8 - 7 - 2 |