Speelschema
| Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|
| 26-11-21 20:30 | 26-11-21 20:30 | VfB Stuttgart | FSV Mainz 05 | 2:1 | 4 - 4 - 3 |
| 27-11-21 15:30 | 27-11-21 15:30 | 1. FC Köln | Bor. Mönchengladbach | 4:1 | 5 - 4 - 3 |
| 27-11-21 15:30 | 27-11-21 15:30 | Hertha BSC | FC Augsburg | 1:1 | 2 - 5 - 6 |
| 27-11-21 15:30 | 27-11-21 15:30 | VfL Wolfsburg | Borussia Dortmund | 1:3 | 5 - 4 - 3 |
| 27-11-21 15:30 | 27-11-21 15:30 | SpVgg Greuther Fürth | 1899 Hoffenheim | 3:6 | 8 - 8 - 2 |
| 27-11-21 15:30 | 27-11-21 15:30 | VfL Bochum | SC Freiburg | 2:1 | 5 - 4 - 3 |
| 27-11-21 18:30 | 27-11-21 18:30 | FC Bayern München | Arminia Bielefeld | 1:0 | 2 - 8 - 8 |
| 28-11-21 15:30 | 28-11-21 15:30 | Eintracht Frankfurt | 1. FC Union Berlin | 2:1 | 3 - 3 - 5 |
| 28-11-21 17:30 | 28-11-21 17:30 | RB Leipzig | Bayer 04 Leverkusen | 1:3 | 3 - 4 - 5 |