Speelschema
| Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|
| 5-11-21 20:30 | 5-11-21 20:30 | FSV Mainz 05 | Bor. Mönchengladbach | 1:1 | 4 - 4 - 3 |
| 6-11-21 15:30 | 6-11-21 15:30 | VfB Stuttgart | Arminia Bielefeld | 0:1 | 2 - 6 - 7 |
| 6-11-21 15:30 | 6-11-21 15:30 | VfL Wolfsburg | FC Augsburg | 1:0 | 2 - 8 - 8 |
| 6-11-21 15:30 | 6-11-21 15:30 | FC Bayern München | SC Freiburg | 2:1 | 2 - 8 - 8 |
| 6-11-21 15:30 | 6-11-21 15:30 | VfL Bochum | 1899 Hoffenheim | 2:0 | 6 - 5 - 3 |
| 6-11-21 18:30 | 6-11-21 18:30 | RB Leipzig | Borussia Dortmund | 2:1 | 3 - 4 - 4 |
| 7-11-21 15:30 | 7-11-21 15:30 | Hertha BSC | Bayer 04 Leverkusen | 1:1 | 5 - 5 - 2 |
| 7-11-21 17:30 | 7-11-21 17:30 | 1. FC Köln | 1. FC Union Berlin | 2:2 | 3 - 4 - 4 |
| 7-11-21 19:30 | 7-11-21 19:30 | SpVgg Greuther Fürth | Eintracht Frankfurt | 1:2 | 7 - 7 - 2 |