Speelschema
| Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|
| 22-10-21 21:00 | 22-10-21 20:59 | FC Arsenal | Aston Villa | 3:1 | 2 - 4 punten |
| 23-10-21 13:30 | 23-10-21 13:29 | FC Chelsea | Norwich City | 7:0 | 2 - 4 punten |
| 23-10-21 16:00 | 23-10-21 15:59 | Crystal Palace | Newcastle United | 1:1 | 2 - 4 punten |
| 23-10-21 16:00 | 23-10-21 15:59 | FC Everton | FC Watford | 2:5 | 2 - 4 punten |
| 23-10-21 16:00 | 23-10-21 15:59 | Leeds United | Wolverhampton Wanderers | 1:1 | 2 - 4 punten |
| 23-10-21 16:00 | 23-10-21 15:59 | FC Southampton | FC Burnley | 2:2 | 2 - 4 punten |
| 23-10-21 18:30 | 23-10-21 18:29 | Brighton and Hove Albion | Manchester City | 1:4 | 2 - 4 punten |
| 24-10-21 15:00 | 24-10-21 14:59 | Brentford FC | Leicester City | 1:2 | 2 - 4 punten |
| 24-10-21 15:00 | 24-10-21 14:59 | West Ham United | Tottenham Hotspur | 1:0 | 2 - 4 punten |
| 24-10-21 17:30 | 24-10-21 17:29 | Manchester United | FC Liverpool | 0:5 | 2 - 4 punten |