Speelschema
| Competitie | Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|---|
| DFB | 6-8-21 20:45 | 6-8-21 20:45 | Dynamo Dresden | SC Paderborn 07 | 2:1 | 2 - 5 punten |
| DFB | 6-8-21 20:45 | 6-8-21 20:45 | TSV 1860 München | SV Darmstadt 98 | 6:5n.p. | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | 1. FC Lokomotive Leipzig | Bayer 04 Leverkusen | 0:3 | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | SV Sandhausen | RB Leipzig | 0:4 | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | SpVgg Bayreuth | Arminia Bielefeld | 3:6 | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | BFC Dynamo | VfB Stuttgart | 0:6 | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | Greifswalder FC | FC Augsburg | 2:4 | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | Wuppertaler SV | VfL Bochum | 1:2n.v. | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | VfL Osnabrück | Werder Bremen | 2:0 | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | Eintracht Norderstedt | Hannover 96 | 0:4 | 2 - 5 punten |
| DFB | 7-8-21 15:30 | 7-8-21 15:30 | SC Weiche Flensburg 08 | Holstein Kiel | 2:4n.v. | 2 - 5 punten |
| DFB | 7-8-21 18:30 | 7-8-21 18:30 | SV Babelsberg 03 | SpVgg Greuther Fürth | 7:6n.p. | 2 - 5 punten |
| DFB | 7-8-21 18:30 | 7-8-21 18:30 | 1. FC Magdeburg | FC St. Pauli | 2:3 | 2 - 5 punten |
| DFB | 7-8-21 18:30 | 7-8-21 18:30 | SSV Ulm 1846 | 1. FC Nürnberg | 0:1 | 2 - 5 punten |
| DFB | 7-8-21 20:45 | 7-8-21 20:45 | SV Wehen Wiesbaden | Borussia Dortmund | 0:3 | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | FC Rot-Weiß Koblenz | Jahn Regensburg | 0:3 | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | Türkgücü München | 1. FC Union Berlin | 0:1 | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | SV Elversberg | FSV Mainz 05 | 9:10n.p. | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | FC Carl Zeiss Jena | 1. FC Köln | 3:5n.p. | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | SV Meppen | Hertha BSC | 0:1 | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | SV Waldhof Mannheim | Eintracht Frankfurt | 2:0 | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | VfL Oldenburg | Fortuna Düsseldorf | 0:5 | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | FC 08 Villingen | FC Schalke 04 | 1:4 | 2 - 5 punten |
| DFB | 8-8-21 15:30 | 8-8-21 15:30 | Preußen Münster | VfL Wolfsburg | 2:0 | 2 - 5 punten |
| DFB | 8-8-21 18:30 | 8-8-21 18:30 | Eintracht Braunschweig | Hamburger SV | 1:2 | 2 - 5 punten |
| DFB | 8-8-21 18:30 | 8-8-21 18:30 | FC Würzburger Kickers | SC Freiburg | 0:1 | 2 - 5 punten |
| DFB | 8-8-21 18:30 | 8-8-21 18:30 | FC Hansa Rostock | 1. FC Heidenheim 1846 | 3:2n.v. | 2 - 5 punten |
| DFB | 9-8-21 18:30 | 9-8-21 18:30 | FC Viktoria Köln | 1899 Hoffenheim | 2:3n.v. | 2 - 5 punten |
| DFB | 9-8-21 18:30 | 9-8-21 18:30 | Sportfreunde Lotte | Karlsruher SC | 1:4 | 2 - 5 punten |
| DFB | 9-8-21 18:30 | 9-8-21 18:30 | FC Ingolstadt | Erzgebirge Aue | 2:1 | 2 - 5 punten |
| DFB | 9-8-21 20:45 | 9-8-21 20:45 | 1. FC Kaiserslautern | Bor. Mönchengladbach | 0:1 | 2 - 5 punten |
| DFB | 25-8-21 20:15 | 25-8-21 20:15 | Bremer SV | FC Bayern München | 0:12 | 2 - 5 punten |